A New Male Contraceptive Created By Compound EP055 May Prevent Sperm From “Swimming”, At Least Temporarily, Study Finds

Male Contraceptive
By Natalia Lusinski | Originally Published April 19, 2018 on Bustle | Featuring Dr. Sherry Ross

As science continues to advance, so, too, does the idea of a male birth control pill. Various researchers have been trying to create a male oral contraceptive for a while now. The latest? A potential male contraceptive pill that may prevent sperm from swimming… at least temporarily. The pill would be created from a compound known as EP055. And it works by binding itself to sperm proteins and slowing the sperm down, reports Medical Daily.

Dr. Michael O’Rand, president and CEO of Eppin Pharma, Inc. and retired professor of cell biology and physiology from the University of North Carolina, was the lead researcher of the study, titled “Inhibition of sperm motility in male macaques with EP055, a potential non-hormonal male contraceptive.” It was just published in the journal PLOS on April 19, 2018.

In fact, in 2004, Dr. O’Rand’s lab at the UNC School of Medicine discovered the protein Eppin, the protein that coats the sperm cell. They then created EP055 that would bind to Eppin — the combo causes the sperm to stop swimming. “Simply put, the compound turns off the sperm’s ability to swim, significantly limiting fertilization capabilities,” Dr. O’Rand told MedicalResearch.com. “This makes EP055 an ideal candidate for non-hormonal male contraception.”

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