Can Pregnant People Get the COVID-19 Vaccine? Here’s Everything We Know So Far
Originally Published on December 11, 2020 Coronavirus | By Claire Gillespie
Pregnant people’s exclusion from clinical trials means we’re missing important information on the safety and efficacy of the vaccine in that potentially high-risk group.
After months of clinical trials, a COVID-19 vaccine appears to be just around the corner. On December 11, Secretary of Health and Human Services, Alex Azar, said the FDA plans to authorize the Pfizer vaccine, and the first shots could be administered as early December 14 or 15.
“Just a little bit ago the FDA informed Pfizer that they do intend to proceed towards an authorization of their vaccine,” Azar told Good Morning America. “We should be seeing the authorization of this first vaccine and… we will work with Pfizer to get that shipped out. We could be seeing people getting vaccinated Monday or Tuesday of next week.”
The Centers for Disease Control and Prevention (CDC) has adopted a recommendation to give the vaccine to health care workers and residents of long-term care facilities before anybody else, since both groups are at an increased risk for contracting the illness, or for developing sever consequences from it.
But what about pregnant people? A Morbidity and Mortality Weekly Report (MMWR) study found that they, too, at increased risk for severe illness from COVID-19, though less so than other high-risk groups. The study found that pregnant people are more likely to be admitted to the intensive care unit (ICU), receive invasive ventilation and extracorporeal membrane oxygenation (the use of an artificial lung located outside the body that puts oxygen into the blood), and are at increased risk of death compared to non-pregnant people. The CDC has also warned that pregnant people with COVID-19 might be at increased risk for other adverse outcomes, such as preterm birth.
So that means pregnant people should get the vaccine too, right?
Unfortunately, it’s not quite as simple as that. Pregnant people haven’t been actively involved in late-stage clinical trials for any COVID-19 vaccines, including the Pfizer and Moderna vaccines. This lack of data means that even when the vaccines are authorized by the FDA for use in the US, they won’t be recommended for pregnant people. On December 2, the Advisory Committee on Immunization Practices (ACIP), the CDC’s independent advisory council, also noted that there is currently “no data on the safety and efficacy of COVID-19 vaccines in [pregnant or breastfeeding people] to inform vaccine recommendations.”
Christopher Zahn, MD, vice president of Practice Activities for the American College of Obstetricians and Gynecologists (ACOG), told Health in an emailed statement that the ACOG had “urged the US Food and Drug Administration as well as the Advisory Committee on Immunization Practices to address use of the vaccine on pregnant and lactating individuals.”
Dr. Zahn added that the ACOG will continue to monitor data and recommendations as they become available and release guidance for members “as soon as enough information is available from FDA and ACIP to adequately inform recommendations for the use of these impending vaccines in pregnant and lactating patients.”
It should be noted that the UK, the first country to approve the Pfizer vaccine, has taken a similar stance regarding pregnant people. In what the UK government describes as a “precautionary approach,” the Joint Committee on Vaccination and Immunisation (JVCI) has advised that pregnant people don’t get the vaccine due to a lack of data on safety. They’ve extended that advice to people who think they may be pregnant and people who are planning a pregnancy within three months of the first dose of the vaccine. | | | Next → |