Can Testosterone Help with Perimenopause Symptoms?

Though often thought of as a “male” hormone, testosterone is important for women too. Produced mainly by the ovaries and adrenal glands, it supports bone strength, mood, cognitive function, and sexual drive.

Because of these roles, researchers and clinicians have explored whether supplementing testosterone can help ease symptoms that arise during the menopause transition.

One of the most significant roles of testosterone in women is its influence on sexual desire and arousal. It also contributes to muscle maintenance and overall wellbeing. Testosterone levels typically peak in a woman’s twenties and then gradually decline, with a more noticeable drop during perimenopause and menopause.

Certain medications, including some hormonal contraceptives and corticosteroids, may also lower testosterone levels.

Signs of Low Testosterone

Low testosterone levels in women may present with:

• Reduced libido
• Low energy
• Loss of muscle mass
• Difficulty conceiving
• Vaginal dryness
• Mood changes such as anxiety or depression
• Thinning hair
• Dry skin
• Sleep disturbances

A blood test is the most reliable way to confirm low testosterone, though symptoms can help guide discussions with a healthcare provider.

Does Testosterone Therapy Help?

Evidence on testosterone therapy is mixed. Some studies suggest it may improve sexual wellbeing in postmenopausal women, including desire, arousal, orgasm, and overall satisfaction. However, long-term safety data are still limited.

For individuals with cardiovascular or liver disease, testosterone therapy may carry additional risks, making it unsuitable in some cases.

Testosterone is more commonly used for menopause-related symptoms in certain countries and is often prescribed off-label elsewhere. It is typically administered through gels or creams applied to the skin.

Healthcare providers who prescribe testosterone usually monitor hormone levels closely and weigh potential benefits against risks.

Possible Side Effects

Potential side effects of testosterone therapy include:

• Acne
• Increased facial or body hair
• Hair thinning on the scalp
• Weight changes
• Clitoral enlargement
• Voice deepening
• Headaches

Some of these effects may be permanent or difficult to reverse, which is why careful monitoring and discussion are essential before starting treatment.

What to Do Next

If you are experiencing symptoms that may be related to hormonal changes, the best first step is to consult your healthcare provider. They can evaluate your symptoms, recommend appropriate testing, and discuss whether testosterone therapy or other treatments may be suitable for you.

In summary, testosterone may help some women during perimenopause, particularly for sexual symptoms. However, it is not appropriate for everyone, and safe use depends on individualized medical evaluation and ongoing monitoring.